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4m
Spinal manipulation vs. exercise for low back pain: A Bayesian analysis
A Bayesian analysis of 120 RCTs shows spinal manipulation offers near-zero benefit for acute back pain. Exercise is superior for chronic pain.
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Groundwork ResearcherBody Research Hub
Clinical Health, Nutrition & Longevity
Clinical nutrition, longevity protocols, sleep science, and supplement label audits — grounded in peer-reviewed evidence.
Interactive Decision Tools (5)
Healthcare Licensure & Clinical Simulators (NEW)
Clinical Health Blueprint14 min read
The Empirical Metabolic & Cardiovascular Health Protocol
A clinical baseline for adults 35–48: Mifflin-St Jeor TDEE energy balance, Tanaka Zone 2/5 cardiovascular training, and 90-minute sleep cycle recovery.
Anchor Decision Calculators:
Core Protocol
Read Full BlueprintThe foundational pillar standard cited across all research cluster articles.
Independent Research Utility
Run the math behind your financial, home, and health decisions
20 interactive calculators with verified formulas, primary government datasets, and zero sponsor bias.
Body Research Guides
199 Verified StudiesExplore guide →
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6m
Cardiovascular risk phenotypes in rheumatoid arthritis: what the data mean for you
Identify six cardiometabolic phenotypes in rheumatoid arthritis and learn how they change your heart disease risk, with actionable steps and a decision matrix.
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Groundwork Researcher
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6m
Machine learning can now map family health histories from electronic records
Machine learning identifies family links in electronic health records with up to 100% precision. Discover how automated pedigrees impact preventive care.
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Groundwork Researcher
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5m
Activated donor immune cells may prevent severe complication after allogeneic stem cell
Discover how activated donor regulatory T cells prevent severe graft-versus-host disease in allogeneic stem cell transplants with rapid 24-hour manufacturing.
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Groundwork Researcher
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8m
Comparative cardiovascular risk profiles: Wheelchair users vs. ambulatory adults in rural
A new cross-sectional study in rural South Africa compares blood pressure and central adiposity between wheelchair users and ambulatory adults to define.
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Groundwork Researcher
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4m
Genetic analyses of blood pressure traits in admixed populations reveal new
Discover how genetic analyses of 140,000 admixed adults reveal new blood pressure variants and improve cardiovascular health insights.
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Groundwork Researcher
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4m
Think you are too young to worry about alzheimers? maria shriver says think again
Discover how Maria Shriver's advocacy and empirical research reveal why women face higher Alzheimer's risk and how early intervention protects brain health.
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Groundwork Researcher
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7m
Digital biomarkers for personalized heat strain monitoring
A new study shows digital biomarkers can distinguish heat stressors with 94.7% accuracy.
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Groundwork Researcher
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4m
Accelerated research, increased investment signal landmark year for food is medicine
Explore how accelerated research and increased investment are making food is medicine a landmark reality for cost-effective chronic disease care.
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Groundwork Researcher
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4m
Hepatitis E virus immunoglobulin G seropositivity and kidney dysfunction among United
Hepatitis E virus IgG seropositivity shows no independent association with kidney dysfunction in US adults after adjusting for age and sex.
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Groundwork Researcher
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8m
How DXA-derived body composition predicts blood pressure in adolescent girls
Study shows DXA-derived fat-to-lean mass ratio strongly predicts hypertensive blood pressure in South African adolescent girls, offering a precise metric for.
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Groundwork Researcher
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7m
Can AI accurately extract psychosis symptoms from clinical notes?
LLMs extract positive psychosis symptoms with 0.500-0.647 F1 accuracy but fail on negative symptoms. Use AI for research, not diagnosis.
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Groundwork ResearcherFrequently Asked Questions & Decision Frameworks
How much protein do I actually need per day?
The RDA of 0.8 g/kg is a floor for survival, not an optimum. Position stands from the ISSN and peer-reviewed reviews support 1.6–2.2 g/kg for active adults preserving muscle while dieting or aging.
Is intermittent fasting better than plain calorie restriction?
Head-to-head trials (NEJM, 2022) found no meaningful fat-loss difference once calories match. Choose the eating pattern you can sustain — adherence drives results, not the clock.
What is the minimum effective exercise dose?
The WHO baseline is 150 minutes of moderate cardio plus two strength sessions weekly. Most cardiovascular benefit arrives between 75–150 minutes per week, with diminishing returns beyond roughly 300.